Systems Biology Solutions

Whether you want to get the basics or fine tune your skills, Clarivate Analytics can help with a variety of targeted training opportunities.

Please contact us if you would like to arrange live training.

Using the Key Pathway Advisor to explore the biological meaning of your gene expression data (45 mins, including Q&A)

This webinar will get you up and running quickly by providing you with what you need to know to use the Key Pathway Advisor (KPA) for predicting upstream regulators (“key hubs”), which could be the root cause of changes in gene expression. KPA also highlights biological pathways which are enriched in predicted key hubs and in your expression data.  In just a few clicks, KPA’s automated workflow can help you with:

  • Identifying drug targets and biomarkers;
  • Understanding disease and drug mechanisms at the molecular level; and
  • Interpreting your results in the context of prior biological knowledge.

To see how simple it is to use the KPA and what it can do for you, click on the link next to your preferred date/time to register for one of our complimentary webinars (45 minutes, including Q&A):

Wednesday, May 10, 2017
3pm UK/16h00 Central Europe/10am East Coast
Wednesday, May 17, 2017
5pm UK/12 noon East Coast/9am West Coast
Wednesday, May 31, 2017
3pm UK/16h00 Central Europe/10am East Coast
Wednesday, June 7, 2017
5pm UK/12 noon East Coast/9am West Coast
Wednesday, June 14, 2017
3pm UK/16h00 Central Europe/10am East Coast
Wednesday, June 21, 2017
5pm UK/12 noon East Coast/9am West Coast

AN UPSTREAM AND DOWNSTREAM SYNERGISTIC APPROACH TO OMICS DATA ANALYSIS USING KEY PATHWAY ADVISOR

  • This webinar will discuss recent trends in bioinformatics approaches to systems and network biology with an additional focus on how biologists use the Key Pathway Advisor (KPA) to analyze and interpret OMICs data. In particular, the root causes of molecular changes in the data along with relationships to prior disease and competitive scientific knowledge will be presented using the KPA analytics.
  • Click to watch

CUSTOM PATHWAY MAP CREATION: RECONSTRUCTING THE ROLE STING PLAYS IN INTERFERON RESPONSE

  • STING, also known as the Stimulator of interferon genes, has been gaining attention lately for its potential as a target for autoimmune, cancer, and anti-viral treatments. In March of 2015 it was announced that Novartis and Aduro Biotech would codevelop a STING modulating compound and by May 2016 the first patients were being dosed in efficacy clinical trials1. Recent research has highlighted the importance of STING’s role in regulating type I interferon pathways, as well as participating in inflammatory responses. Combining the knowledge from this growing body of published research into the context of an interaction pathway can be a powerful tool for analyzing data and sharing knowledge. In these webinar, we will be using a combination of network building and the Pathway Map Creator in MetaCore to answer these questions:
    • How are neighboring biological interactors around STING related to each other?
    • How do I build a custom pathway map detailing the interaction network I’ve built?
    • How do I overlay datasets or run enrichment analysis with these novel pathway maps?
  • Click to watch

PERSONALIZED CANCER TREATMENT AND PATIENT STRATIFICATION USING NGS AND OTHER OMICS DATA

During this webinar, informatics specialists and oncologists from the European Society of Medical Oncology (ESMO), the University of Maryland, and Thomson Reuters discuss the applications of a novel and comprehensive set of knowledge resources and analytical tools.

RECONSTRUCTION OF DISEASE PATHOLOGY FOR DRUG DISCOVERY: FOCUS ON RESPIRATORY DISEASES (ASTHMA AND COPD)

During this webinar, respiratory disease experts and Thomson Reuters will discuss:

  • Different aspects of asthma and COPD biology and challenges in disease research
  • Applicability of disease pathway analysis tools in clinical and fundamental disease research
  • Main features and content of the ongoing MetaMiner Respiratory Diseases project
  • Case studies featuring use of disease reconstruction in drug discovery
  • Industry member perspective on disease partnerships in the respiratory area