Integrity

Thomson Reuters IntegritySM provides researchers with reliable, detailed information, from the perspective of a scientist, across multiple disciplines to support successful drug research and development.

By integrating biological, chemical and pharmacological data on more than 320,000 compounds with demonstrated biological activity and almost 140,000 patent family records, Integrity provides a unique knowledge solution designed to empower your discovery and development activities where you need it most — at the bench.

Whether you want to get the basics and get started fast — or fine tune your skills, Thomson Reuters can help with a variety of targeted training opportunities. Classes are conducted over the internet — some live with open question-and-answer sessions — and others prerecorded so you can take advantage of them at your convenience, around the clock.

We invite you to explore the following Integrity training opportunities.

E-Learning

Integrity: Getting Started

A brief overview of the Integrity homepage, as well as how to use the Quick Search and also how to search in a specific Knowledge Area and analyze the results found.

 

Integrity: Biomarkers Module

NEW. Watch how a team of scientists use Thomson Reuters Biomarker Solutions to identify new markers of Alzheimer's Disease progression, giving them a better understanding of the disease and helping them prioritize their research activities.

Learn how to find biomarkers for monitoring treatment efficacy for a specific disease.

 

Integrity: Experimental Models

Learn how to find experimental models of a specific disease in Integrity

 

Integrity: Exporting data and structures

Learn how to export a list of drugs in Integrity, including their chemical structures and also related references, pharmacology, PK and clinical studies data.

 

Integrity: Structure Searching

Learn how to access the structure editors in Integrity and how to set up a specific structure search, as well as how to export or copy the chemical structures retrieved.

 

Integrity: Targets & Pathways

Learn how to find targets associated to a specific disease and how to link to the drugs that act via those targets.

Use Cases

Use Cases are examples created by our scientists that demonstrate how Integrity can be used in real situations. Step-by-step instructions guide users through the database stimulating ideas of how to apply its vast potential to find solutions to the issues they are facing.

INFLUENZA A: A New Challenging Opportunity for Market Impact PPT
This use case will focus on this challenging disease in terms of marketed products and current development pipeline, sales impact and new opportunities in synthesis and for chemical intermediates.
Areas covered: Disease Briefings / Organic Synthesis / Drugs & Biologics

LEUKEMIA THERAPY: Bcr-Abl Kinase Inhibitors PPT
This use case will focus on compounds used to fight leukemia, structures will be analyzed and compounds with similar structures will be found. Targets will also be investigated.
Areas covered: Drugs & Biologics/Targets & Pathways

INTEGRITY QUICK GUIDES:

See our library of Quick Guides sorted by Knowledge Area and do not miss the TIPS & TRICK section to make the most of the Integrity interface.

DRUGS & BIOLOGICS

TARGETS & PATHWAYS

GENOMICS

BIOMARKERS

ORGANIC SYNTHESIS

EXPERIMENTAL PHARMACOLOGY

EXPERIMENTAL MODELS

PHARMACOKINETICS/METABOLISM

DISEASE BRIEFINGS

LITERATURE

PATENTS

TIPS & TRICKS ON THE INTEGRITY INTERFACE

MORE INFORMATION ABOUT THOMSON REUTERS INTEGRITY